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This method, coupled with its ability to improve insulin sensitivity, adds a valuable tool in the arsenal against obesity, especially when used in conjunction with other lifestyle modifications.โ โ Kelsey Costa, MS, RDN She added that โthe extension of fasting periods to ranges between 18 to 72 hours could significantly delay the onset of a weight loss plateau by further enhancing the bodyโs metabolic adaptability.โ Costa further cautioned that โ[t]his study uses mathematical modeling to simulate how different obesity treatments might impact body weight, composition, and energy balance dynamics without testing these interventions in real-life scenarios.โ โThe present study did not explore dietary interventions beyond calorie or macronutrient restrictions, leaving room for future research into the comprehensive effects of various weight-loss strategies,โ she pointed out