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In addition, AOPPs upregulate the Wnt/β-catenin pathway through the receptor for advanced glycation end-products (RAGE) receptor, contributing to podocyte dysfunction [60]

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Likewise, within a meta-analysis encompassing 22,961 individuals afflicted with diabetes, the utilization of DPP-IV inhibitors exhibited no discernible linkage with a diminishment in fractures (Driessen et al., 2017)