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The exploratory end points were PD parameters, including concentrations of fasting glucose, insulin, C-peptide, glucagon, free fatty acid, lipids, HbA1c and changes in BW, waist circumference and BMI

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Nel trial MAESTRO-NASH ha dimostrato la risoluzione della MASH senza peggioramento della fibrosi nel 26–30% dei pazienti, rispetto al 9,7% del placebo (Harrison et al., 2024)