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Proinflammatory mediators such as interleukin-6 (IL-6), interleukin-1 (IL-1), and LPS have also been reported to directly stimulate GLP-1 secretion from intestinal endocrine L cells
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WeightWatchers’ removal from the NHS Diabetes Prevention Programme in 2022 raises questions about their non-medication approach, though their GLP-1 programme is a different and newer offering
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