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Setmelanotide in obesity: a profile of its use | Drugs & Therapy Perspectives | Springer Nature Link

Sorensen also points out that people should use their ideal or goal body weight—not their current body weight—when calculating how much protein to eat

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Fear of long-term effects: Given the ongoing discussions about risks in the medical community, some patients may have concerns about the long-term impact of GLP-1 medications, including dangerous adverse reactions as described on the FDA warning label, like acute kidney injury and hypoglycemia