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The Frontier of Metabolic Health: High-Dose Oral Semaglutide Redefines Diabetes and Obesity Care | Pharmacy Times

Single-nucleus RNA-sequencing shows opposing effects of GIPR agonism and antagonism in the hindbrain, with antagonism, but not agonism, mimicking GLP-1R signalling and with GIPR antagonism and GLP-1R agonism both regulating gene programmes implicated in synaptic plasticity

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Glucose homeostasis and insulin secretion models: Evaluation of glucose-dependent insulin secretion , glucagon modulation , and glucose tolerance in pancreatic islet systems and intact animal models