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➡️ ↓ Cholesterol absorption ➡️ ↓ Hepatic cholesterol stores ➡️ ↑ Hepatic LDL receptor activity ➡️ ↓ LDL cholesterol in the blood 💡 Drug Class: Cholesterol absorption inhibitor 📌 Common Uses • Primary hypercholesterolemia • Mixed dyslipidemia • As an add-on to statin therapy when additional LDL-C reduction is needed • Statin-intolerant patients in selected cases 💊 Typical adult dose: 10 mg once daily ⚠️ Pharmacist Tip: Ezetimibe has a different mechanism from statins, making it a useful combination option when LDL-C targets are not achieved with statin therapy alone
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GLP‐1 receptor agonists prevented ‘relapse’ to binge‐like alcohol drinking after deprivation and attenuated alcohol withdrawal‐induced anxiety‐like behaviour (Sharma et al., 2015b