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Among over 500 obese patients with OSAS, long-term tirzepatide treatment led to significant reductions in body weight, AHI, and oxygen desaturation index, with particularly pronounced benefits in patients with concurrent glucose and lipid metabolism abnormalities (52)
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Future perspectives and outstanding questions Despite substantial progress, several unmet needs and key questions require investigation to fully realize the therapeutic potential of GLP-1-based therapies in MASLD/MASH