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Systemic hormone effects: GLP-1 receptors exist throughout the body, including in the heart, blood vessels, kidneys, and liver
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“The turning point came around 2015, when higher-dose liraglutide, under the brand name Saxenda, was approved for obesity, confirming the weight loss effect wasn’t just a side effect, but a primary therapeutic action.” GLP-1s worked differently from earlier diet drugs
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