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Other Weight Loss Prescription Options: Qsymia (phentermine-topiramate): A combination medication that suppresses appetite and increases feelings of fullness Contrave : Works on brain pathways involved in hunger and cravings Weight Loss Surgery Options For those with significant obesity or weight-related health conditions, bariatric surgery might be a more viable solution: Gastric Sleeve : Removes approximately 80% of the stomach Gastric Bypass : Creates a small stomach pouch and reroutes the digestive tract 4