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The Mechanism: How GLP-1s Influence Reward and Cravings Dopamine Pathway Modulation: Hitting the Brain's Reward Centers Reducing the Pleasure/Reinforcement Associated with Alcohol Because alcohol normally induces a large dopamine release, which creates a pleasurable sensation throughout the body, when taking GLP-1s, it counteracts this effect, which causes the consumer to experience less pleasure or reward from alcohol, which can reduce the will to drink it

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