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“At our center, exposure calls have steadily increased since 2022 and, as of mid-June 2026, we have already managed around 130 exposures so far this year.” While most poison center calls often reflect dosing slip-ups, questions about side effects and proper medication use, Susan Wolver, M.D., clinic director of the VCU Health Medical Weight Loss Program, has seen a rise in another safety concern on social media

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However, patients tend to tolerate these side effects because of the significant weight loss benefits they experience - something metformin does not offer