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et al., 2024), GLP-1 RAs function as incretin mimetics, stimulating insulin release by pancreatic β-cells in a glucose-dependent manner while suppressing glucagon secretion from α-cells (Figure 1)
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32,33 However, given the lack of comprehensive reviews in the existing literature on the pharmacokinetics and drug-drug interactions (DDIs) of GLP-1 RAs and a dual GLP-1/GIP RA, we produced this review to consolidate current knowledge and provide a thorough analysis of key considerations in clinical practice
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