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Using molecular approaches, these studies described differential expression of voltage-gated ion channels – including sodium (Nav), potassium (Kv), and calcium (Cav) channels in Glutag cells and purified colonic L-cells (Rogers et al., 2011)

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In contrast, long-acting GLP-1 RAs, including exenatide long-acting release (exenatide LAR), liraglutide, dulaglutide, and semaglutide, provide more sustained reductions in fasting plasma glucose (FPG) by continuously enhancing insulin secretion and suppressing glucagon release [72]