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The sequences of miR-5120 mimic, miR-5120 inhibitor, GLP-1R siRNA and their controls are shown in Supplementary Table 1

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A more conservative approach may be worth discussing with a provider if you have a history of GI sensitivity or conditions like IBS, have previously stopped GLP-1 therapy because of side effects, are an older adult (who may be more sensitive to GI effects), or are starting treatment at a lower BMI where the full therapeutic dose may not be necessary