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Clinical Application of Glucagon-Like Peptide 1 Receptor Agonists for the Treatment of Type 2 Diabetes Mellitus

doi: 10.1016/S0140-6736(21)00213-0 [DOI] [PubMed] [Google Scholar] 74

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While sulphonylureas potently promote insulin secretion in type-2 diabetic patients via inhibition of K ATP channel activity [[267], [268], [269], [270]], there is no clear evidence that sulphonylureas affect GLP-1 secretion in humans (as reviewed in [266])