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When Madeson shared his data with Knudsen in 1995, she realised that it rang a bell because she had noticed that both normal and obese rates experienced a lasting and reversible weight loss when given one of her early GLP-1 analogues
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34 Unfortunately, we lacked systematic access to glycated haemoglobin values, which could have indicated that cases in our study population were with well-managed diabetes inadvertently selected leading to a rate of birth defects similar to the general population