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Wegovy (semaglutide) functions primarily as a GLP-1 receptor agonist that increases insulin production, decreases glucagon secretion, and slows down gastric emptying
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In vivo, however, the nonnutritive sweeteners sucralose (in humans and animals) and acesulfame, stevia, and d-tryptophan (in animals) do not stimulate GLP-1, GIP, or PYY secretion in the absence of caloric sugars (18,19)
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