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By examining how these agents interact with key nodes of the reward circuitry—particularly within the mesocorticolimbic dopamine system—we aim to elucidate the mechanisms through which GLP-1 signaling may attenuate drug-seeking behavior, reduce relapse vulnerability, and modulate craving
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Liraglutide, a longer acting GLP-1RAs, has also shown promising results in terms of reductions in alcohol intake, self-administration, and alcohol preference in rats [57, 58]
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