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Stimulate GLP-1 release Improve insulin sensitivity Support glucose regulation Statins reduce cholesterol production, which can : Change bile acid composition Reduce stimulation of these GLP-1-activating receptors Result in lower GLP-1 secretion 2️⃣ Changes in the gut microbiome Statins are consistently shown to alter gut bacteria — sometimes beneficially, sometimes not

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The muscle preservation imperative This point deserves repeating because it is that important