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While earlier evidence suggested GIP agonism may exacerbate GI adverse events (Min and Bain, 2021), recent preclinical and clinical studies indicate it may reduce nausea and vomiting, though its effect on diarrhea is less pronounced
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“Mounjaro has to be titrated when it is started, meaning a gradual dose increase happens over many months, to allow the body to adjust to the medication and lower the risk of side effects,” says Florencia Halperin, MD, a Boston-based endocrinologist who is the chief medical officer of the weight loss clinic Form Health
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