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doi: 10.1002/psc.1328 71 BianchiECarringtonPEIngallinellaPFinottoMSantopreteAPetrovAet al

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Role of GLP-1R binding kinetics The length of time that an agonist remains bound to its receptor, or residence time, is an important factor influencing the duration of drug action and a suggested driver of sustained signaling from internalized receptors 7