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They also found that treatment with exenatide resulted in a marked increase in anti-inflammatory cytokines (IL-4 and IL-10) alongside a reduction in pro-inflammatory cytokines (TNFα and IL-1β) [65]

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Unlike prescription GLP-1 drugs such as semaglutide (Ozempic, Wegovy) or tirzepatide (Mounjaro, Zepbound), these supplements lack rigorous clinical evidence and regulatory oversight

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