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Second-generation oral semaglutide, whose bioavailability and safety have been significantly improved by the application of new excipients and formulation optimization, but its gastrointestinal side effects are still obvious (Nielsen et al., 2025)
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Quick Answer: Nausea and vomiting are common side effects of Zepbound, affecting 24-29% and 6-12% of patients respectively, typically improving over time as the body adjusts to treatment
