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Immunohistochemical analysis revealed that GLP1R protein ( Figure 1O ) was not expressed in MC38 tumors (no validated antibody currently exists for murine GIPR 35 ), consistent with our analysis of the Cancer Cell Line Encyclopedia database 36 showing 0/80 human colorectal cancer cell lines and 2/66 human breast cancer cell lines (and only 22/1437 of all human cancer cell lines) express GLP1R at appreciable levels 37 ( Figure 1P )
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Size:180 Tablet
Based on individual patient response and tolerability, the dose may be further titrated in 2.5mg increments every four weeks, up to a maximum of 15mg per week