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The article states plainly that gastrointestinal tolerability often determines treatment adherence, and says these events frequently improve as the dose is titrated under provider supervision and with patient education
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Additively, more patients with OSA in the EMPA arm received either diuretics ( n = 170) or metformin (MET, n = 188) than those in the placebo arm ( n = 74 and n = 81, respectively), which could affect body weight differences
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