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Prolonged and enhanced secretion of glucagon-like peptide 1 (7-36 amide) after oral sucrose due to alpha-glucosidase inhibition (acarbose) in Type 2 diabetic patients

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When gut bacteria ferment dietary fiber, they produce short-chain fatty acids (SCFAs) such as butyrate, propionate, and acetate, and in laboratory and human studies these metabolites can prompt gut L-cells to release GLP-1