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This, combined with the inevitable change in diet that comes from decreased hunger (and, frequently, a shift to healthier foods to support the smaller diet and fight malnutrition), can throw your gut biome into disarray
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It notes gastrointestinal effects like nausea, vomiting, constipation, and diarrhea are dose-dependent, so piling on a second GLP-1 makes tolerability and adherence worse
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