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CCH is an injectable drug, first of its class, and is composed of two purified bacterial collagenases (AUX-I and AUX-II [Clostridial class I and II collagenases]) that hydrolyze Type I and III collagen with high specificity under physiologic conditions, resulting in disruption of targeted collagen structures found within the septae of cellulite
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This necessitates frequent dosing to maintain potentially therapeutic plasma concentrations
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