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contraindications for glp 1 agonists include Who Should Not Take GLP-1 Medication? Clinical – PlexusDx Incidence of hematologic malignancies
Incidence of hematologic malignancies and mortality associated with GLP-1 receptor agonist and SGLT2 inhibitor use in type 2 diabetes mellitus: results of a retrospective cohort study of electronic health records - eClinicalMedicine
The mechanism of action of the DPP-4 inhibitors raises the question: Will these agents be effective in patients who have had diabetes for 10 to 15 years and who may no longer have any beta-cell function
The industry perspective partly aligns here: manufacturers want labels that fairly represent risk without undue alarm
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