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A 2024 analysis of 2,890 patients on once-weekly GLP-1 therapy (Blonde et al., Diabetes Therapy ) found that patients who selected a consistent morning time window (6 AM to 10 AM) had 22% better on-time dosing rates (defined as within 24 hours of scheduled day) compared to evening dosers (6 PM to 10 PM) over the first 16 weeks of treatment

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