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The expanding scope of GLP-1 receptor agonists: Six uses beyond diabetes - PMC

A generic that captures a high-spend small molecule with 180-day exclusivity may face only one competitor for six months, allowing pricing at 70-80% of brand WAC rather than the 10-20% that comes later when seven or eight generics are on market

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If you resume smoking while on tirzepatide, the medication may still reduce craving intensity compared to baseline, but it won’t prevent relapse if behavioural triggers or withdrawal symptoms overwhelm its dopamine-modulating effect