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In three separate SUSTAIN trials, semaglutide 1 mg conferred a greater weight loss among adults with type 2 diabetes than exenatide 2 mg (Bydureon, AstraZeneca), dulaglutide 1.5 mg (Trulicity, Eli Lilly) and liraglutide 1.8 mg (Saxenda, Novo Nordisk)

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Zepbound, from drugmaker Eli Lilly, belongs to a new class of medications, called GLP-1 agonists, that have skyrocketed in popularity in the U.S