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To exclude any artifacts from an irreversible interaction between β-arrestin and receptor in the PathHunter assay, we visualized GFP-tagged β-arrestin-2 in MIN6B1-SNAP-GLP-1R cells, showing that exendin-4 and exendin-asp3, but not exendin-phe1, induce robust translocation to SNAP-GLP-1R-positive PM and endosomes (Fig
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Glucagon is a hormone that, paradoxically, can increase energy expenditure and promote feelings of fullness when activated in combination with GLP-1