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The brand-name versions of this drug (Byetta and Bydureon BCise) were discontinued , but a generic version became available in late 2024
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Substitution studies indicate that the electrostatic, steric, and conformational properties of the four residues following the N-capping motif of GLP-1 (His 7 , Ala 8 , Glu 9 , Gly 10 ) are important determinants for GLP-1R binding and/or activation