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Modulate cell signaling: GLP-1 RAs boost cAMP activity while reducing ERK and MAPK pathways, which are often overactive in cancer
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33 Thus, with patients presenting for consideration for surgery, it is important for the surgeon to prioritize counseling patients regarding adequate weight-based protein intake for 2–4 weeks before surgery and for another 4 weeks postoperatively for optimal perioperative optimization and outcomes
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