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doi: 10.1056/NEJMoa1812389 10 NealBPerkovicVMahaffeyKWde ZeeuwDFulcherGEronduNet al
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The review revisited SUSTAIN-6, where semaglutide-treated patients showed a hazard ratio of 1.76 for retinopathy complications compared with placebo.² The discussion has since shifted toward whether rapid metabolic change—rather than direct retinal toxicity—may explain the signal
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