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doi: 10.3389/fimmu.2026.1744308 Received 11 November 2025 Revised 04 April 2026 Accepted 13 April 2026 Published 28 April 2026 Volume 17 - 2026 Edited by Francesco Caso, University of Naples Federico II, Italy Reviewed by Piero Ruscitti, University of L’Aquila, Italy Silvia Scriffignano, Fondazione Istituto G.Giglio, Italy Updates Copyright © 2026 Ciancio, Maranini, Sandri, Amati, Bortoluzzi, Silvagni, Govoni and Giuggioli