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However, in this case, there are numerous obstacles to cross, mainly financial and resource barriers, intellectual properties, data access barriers, biases, and liability risks ( Numerous collaborative initiatives with the final aim of drug repurposing were objects of debate, among wich: The AZ Open Innovation program, the NIH National Center for Advancing Translational Sciences (NCATS) program: Discovering New Therapeutic Uses for Existing Molecules, the Medical Research Council (MRC) and AstraZeneca (AZ) Mechanisms of Human Disease Initiative, The Clinical and Translational Science Award (CTSA) Pharmaceutical Assets Portal, European College of Neuropsychopharmacology (ECNP) Medicines Chest Program, Pfizer’s SpringWorks Program, the AstraZeneca/National Research Program for Biopharmaceuticals (NRPB) partnership in Taiwan, the Roche/Broad Institute Collaboration, and the Drugs for Neglected Diseases Initiative (DNDI), the Clinical Development Partnerships Initiative ( Some examples of drugs that have been repositioned for the treatment of certain types of cancer over the years include Sunitinib, a drug that was successfully repositioned for the treatment of gastrointestinal stromal tumors and renal cancers
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