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In a rat model of insulin resistance and obesity, empagliflozin regulates mitochondrial dynamics, increasing fusion protein mitofusin-2 (MFN2) expression, while decreasing the levels of the fission protein dynamin-related protein 1 (DRP1) in white adipose tissue [120]
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The same goes for people with a condition called gastroparesis, which affects stomach nerves and muscles, and those susceptible to medullary thyroid cancer