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The appetite-suppressive effects create a secondary concern: patients taking both drugs may inadvertently restrict calories to unsafe levels, leading to nutrient deficiencies, muscle loss, or metabolic adaptation that undermines long-term weight loss
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[DOI] [PubMed] [Google Scholar] 101.Disse E., Bussier A.L., Veyrat-Durebex C., Deblon N., Pfluger P.T., Tschöp M.H., Laville M., Rohner-Jeanrenaud F